Writer's cramp: Treatment with botulinum toxin injections
Identifieur interne : 006112 ( Main/Exploration ); précédent : 006111; suivant : 006113Writer's cramp: Treatment with botulinum toxin injections
Auteurs : J. Rivest [Royaume-Uni] ; Andrew Lees (neurologue) [Royaume-Uni] ; Marsden [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 1991.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Adult, Botulinum Toxins (administration & dosage), Botulinum toxin, Chemotherapy, Clostridium botulinum, Dystonia, Dystonia (drug therapy), Extrapyramidal syndrome, Female, Handwriting, Human, Humans, Injections, Intramuscular, Intramuscular administration, Involuntary movement, Male, Middle Aged, Muscle Cramp (drug therapy), Nervous system diseases, Neurologic Examination, Toxin, Treatment, Writer cramp, Writer's cramp.
- MESH :
- chemical , administration & dosage : Botulinum Toxins.
- drug therapy : Dystonia, Muscle Cramp.
- Adult, Female, Handwriting, Humans, Injections, Intramuscular, Male, Middle Aged, Neurologic Examination.
Abstract
Twelve patients with writer's cramp were treated with injections of botulinum toxin. The overactive muscles were identified by clinical observation of the subjects while they were writing. Repeated injections were given at 2‐week intervals until the optimal response was obtained. Eleven patients reported some benefit, which was considered by seven to be significant. Eight of the 10 patients who had pain reported moderate to significant relief. Five patients had local complications, consisting of disabling weakness of target or neighbouring muscles. These preliminary results suggest that this treatment can be successfully applied to many patients with writer's cramp without performing complex electromyographic recordings while the patients are writing.
Url:
DOI: 10.1002/mds.870060110
Affiliations:
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Le document en format XML
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<wicri:cityArea>University Department of Clinical Neurology, Institute of Neurology, The National Hospital, Queen Square, London</wicri:cityArea>
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<author><name sortKey="Lees, A J" sort="Lees, A J" uniqKey="Lees A" first="A. J." last="Lees">Andrew Lees (neurologue)</name>
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<series><title level="j">Movement Disorders</title>
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<term>Botulinum Toxins (administration & dosage)</term>
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<term>Chemotherapy</term>
<term>Clostridium botulinum</term>
<term>Dystonia</term>
<term>Dystonia (drug therapy)</term>
<term>Extrapyramidal syndrome</term>
<term>Female</term>
<term>Handwriting</term>
<term>Human</term>
<term>Humans</term>
<term>Injections, Intramuscular</term>
<term>Intramuscular administration</term>
<term>Involuntary movement</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Muscle Cramp (drug therapy)</term>
<term>Nervous system diseases</term>
<term>Neurologic Examination</term>
<term>Toxin</term>
<term>Treatment</term>
<term>Writer cramp</term>
<term>Writer's cramp</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Botulinum Toxins</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Dystonia</term>
<term>Muscle Cramp</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Female</term>
<term>Handwriting</term>
<term>Humans</term>
<term>Injections, Intramuscular</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neurologic Examination</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Chimiothérapie</term>
<term>Clostridium botulinum</term>
<term>Crampe écrivain</term>
<term>Dystonie</term>
<term>Extrapyramidal syndrome</term>
<term>Homme</term>
<term>Mouvement involontaire</term>
<term>Système nerveux pathologie</term>
<term>Toxine</term>
<term>Traitement</term>
<term>Voie intramusculaire</term>
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<front><div type="abstract" xml:lang="en">Twelve patients with writer's cramp were treated with injections of botulinum toxin. The overactive muscles were identified by clinical observation of the subjects while they were writing. Repeated injections were given at 2‐week intervals until the optimal response was obtained. Eleven patients reported some benefit, which was considered by seven to be significant. Eight of the 10 patients who had pain reported moderate to significant relief. Five patients had local complications, consisting of disabling weakness of target or neighbouring muscles. These preliminary results suggest that this treatment can be successfully applied to many patients with writer's cramp without performing complex electromyographic recordings while the patients are writing.</div>
</front>
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<orgName><li>National Hospital for Neurology and Neurosurgery</li>
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<tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Rivest, J" sort="Rivest, J" uniqKey="Rivest J" first="J." last="Rivest">J. Rivest</name>
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